Book Hotels in Southeast Iowa

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Southeast Iowa hotels

Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison

2.5 out of 5
4901 Avenue O, Fort Madison, IA
Fully refundable
$75 nightly
The price is $84 total per night from Oct 8 to Oct 9
$84 total
Oct 8 - Oct 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
"AC great. Breakfast super. Staff kind and most helpful."

Reviewed on Oct 3, 2025

Opens in a new windowCobblestone Inn & Suites - Fort Madison
The Catfish Bend Inn & Spa

The Catfish Bend Inn & Spa

3.5 out of 5
3001 Winegard Dr, Burlington, IA
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $178 total per night from Oct 31 to Nov 1
$178 total
Oct 31 - Nov 1
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and a water park. There's fun for all ages with a lazy river and a waterslide. Enjoy a meal in one ...
"Beautiful entertainment complex. So much to offer under one roof."

Reviewed on Sep 23, 2025

Opens in a new windowThe Catfish Bend Inn & Spa
Nauvoo Temple House Hotel

Nauvoo Temple House Hotel

2 out of 5
1200 Mulholland St, Nauvoo, IL
$99 nightly
The price is $112 total per night from Nov 1 to Nov 2
$112 total
Nov 1 - Nov 2
Total with taxes and fees
Free WiFi in public areas is available at this hotel. Take advantage of the free self parking.
"I was so surprised at what a hidden gem this was. Recently updated and super clean. Very spacious."

Reviewed on Oct 4, 2025

Opens in a new windowNauvoo Temple House Hotel
Comfort Suites Burlington

Comfort Suites Burlington

2.5 out of 5
1780 Stonegate Center Dr, Burlington, IA
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $128 total per night from Nov 2 to Nov 3
$128 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. A 24-hour business center, free WiFi ...
"The place was great, did have a problem with the TV but the staff was quick to fix it!"

Reviewed on Sep 29, 2025

Opens in a new windowComfort Suites Burlington
Fun City Resort Hotel

Fun City Resort Hotel

3.5 out of 5
3001 Winegard Drive, Burlington, IA
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $188 total per night from Oct 8 to Oct 9
$188 total
Oct 8 - Oct 9
Total with taxes and fees
This Art Deco hotel features a casino, a water park, and a restaurant. Bring the family and enjoy the lazy river, free kid's club, and kid-friendly dining. Enjoy ...
"It was over all a good experience Maybe someday I'll come back"

Reviewed on Sep 29, 2025

Opens in a new windowFun City Resort Hotel
Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North

2.5 out of 5
3404 Main St, Keokuk, IA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Nov 4 to Nov 5
$110 total
Nov 4 - Nov 5
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"I was a little upset our bathroom was in poor shape. I booked this trip all the way back in march. The room was well appointedl but the bathroom had mold growth, caulk was coming off the shower and tub and paint was bubbling on the wall . Looked like a more recent flood or something but it was not ..."

Reviewed on Oct 3, 2025

Opens in a new windowQuality Inn & Suites Keokuk North
Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Fort Madison near Hwy 61

2.5 out of 5
6169 Reve Ct, Hwy 61 & Hwy 2, Fort Madison, IA
$85 nightly
The price is $95 total per night from Oct 26 to Oct 27
$95 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Very clean. Comfortable. Bar/restaurant across the street."

Reviewed on Oct 4, 2025

Opens in a new windowQuality Inn & Suites Fort Madison near Hwy 61
Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn

2.5 out of 5
810 N Grand Avenue, Mount Pleasant, IA
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Oct 13 to Oct 14
$81 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with ...
"Was fine for an overnight stop"

Reviewed on Sep 11, 2025

Opens in a new windowBest Western Mt. Pleasant Inn
Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk

2.5 out of 5
325 Main St, Keokuk, IA
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $67 total per night from Oct 12 to Oct 13
$67 total
Oct 12 - Oct 13
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. ...
"Slightly outdated with limited extra seating. Adequate and clean, heating & cooling effective."

Reviewed on Sep 28, 2025

Opens in a new windowBaymont by Wyndham Keokuk
Don't see what you're looking for?
See all available properties in Southeast Iowa
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Iowa hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southeast Iowa hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity