Book Hotels in Southeast Iowa

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Southeast Iowa hotels

Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison

2.5 out of 5
4901 Avenue O Fort Madison IA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $112 total per night from Apr 19 to Apr 20
$112 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
I had never stayed at a Cobblestone hotel prior to this, and I was pleasantly surprised. It met my expectations in every way, including cleanliness, ease of parking, nice open lobby/breakfast room and pleasant staff. Becky checked me in and gave me great information for our stay in Fort Madison. ...

Reviewed on Apr 12, 2026

Opens in a new windowCobblestone Inn & Suites - Fort Madison
The Catfish Bend Inn & Spa

The Catfish Bend Inn & Spa

3.5 out of 5
3001 Winegard Dr Burlington IA
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $173 total per night from Apr 19 to Apr 20
$173 total
Apr 19 - Apr 20
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and a water park. There's fun for all ages with a lazy river and a waterslide. Enjoy a meal in one ...
They need to get rid of smoking completely in the casino

Reviewed on Apr 5, 2026

Opens in a new windowThe Catfish Bend Inn & Spa
Comfort Suites Burlington

Comfort Suites Burlington

2.5 out of 5
1780 Stonegate Center Dr Burlington IA
Fully refundable
$110 nightly
The price is $124 total per night from May 10 to May 11
$124 total
May 10 - May 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. A 24-hour business center, free WiFi ...
Clean room. Breakfast was warm. Kids loved the pool.

Reviewed on Apr 14, 2026

Opens in a new windowComfort Suites Burlington
AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant

2 out of 5
1100 N Grand Ave Mount Pleasant IA
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $87 total per night from Apr 23 to Apr 24
$87 total
Apr 23 - Apr 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Clean rooms, friendly staff, breakfast was good.

Reviewed on Mar 30, 2026

Opens in a new windowAmericInn by Wyndham Mount Pleasant
Fun City Resort Hotel

Fun City Resort Hotel

3.5 out of 5
3001 Winegard Drive Burlington IA
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $188 total per night from Apr 19 to Apr 20
$188 total
Apr 19 - Apr 20
Total with taxes and fees
This Art Deco hotel features a casino, a water park, and a restaurant. Bring the family and enjoy the lazy river, free kid's club, and kid-friendly dining. Enjoy ...
The hotel was great. Everyone was helpful and kids had a great time.

Reviewed on Apr 4, 2026

Opens in a new windowFun City Resort Hotel
Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Fort Madison near Hwy 61

2.5 out of 5
6169 Reve Ct Fort Madison IA
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $103 total per night from Apr 26 to Apr 27
$103 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Tv didn't work in the first room we were in so they moved us to another room. The hot tub wasn't working which was originally the reason we chose there hotel but since it was my daughter's birthday and she wanted to swim we stayed. Also the pool was really cold and the exercise room was ...

Reviewed on Apr 17, 2026

Opens in a new windowQuality Inn & Suites Fort Madison near Hwy 61
Quality Inn & Suites Mount Pleasant

Quality Inn & Suites Mount Pleasant

2.5 out of 5
1200 E Baker St Mount Pleasant IA
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $77 total per night from Apr 23 to Apr 24
$77 total
Apr 23 - Apr 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
The staff is always very helpful and friendly and always willing to work with you. Would highly recommend.

Reviewed on Apr 17, 2026

Opens in a new windowQuality Inn & Suites Mount Pleasant
Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn

2.5 out of 5
810 N Grand Avenue Mount Pleasant IA
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $87 total per night from Apr 27 to Apr 28
$87 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with ...
Check in was quick and easy, the hotel is clean, and everyone on staff was friendly and helpful.

Reviewed on Apr 13, 2026

Opens in a new windowBest Western Mt. Pleasant Inn
AmericInn by Wyndham West Burlington

AmericInn by Wyndham West Burlington

2.5 out of 5
628 S Gear Ave West Burlington IA
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Apr 26 to Apr 27
$75 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Families will appreciate the arcade/game ...
When I arrived it was only one staff who was over worked. You could see that he was overwhelmed. When I checked in got into to my room it wasn't cleaned, bedding on the floor no trash bags in the trash cans the room a mess. Then when I reported it was more like "let me see if I can upgrade you, the ...

Reviewed on Apr 16, 2026

Opens in a new windowAmericInn by Wyndham West Burlington
Don't see what you're looking for?
See all available properties in Southeast Iowa
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Iowa hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southeast Iowa hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity